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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ff221375fa4a1f233cba73b01d2b0677fb2d4d882f9ac31779a91aaa0d01d34' 
  AND token = 'wsDXWYnLSfnXMDH9dMQy6HthP0r7KSKGUywjE0H3Qso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}