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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b3e66abaef914f56bb34bc1cd443ce3612e0184e88d0052e3e864ac3649d5f7' 
  AND token = '/89IvusEg0+NawTZNwc7606AV26VjDCwjuuw3cXMRZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}