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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d566f54b4ab901f0ba2aa0c786801e991e8de28376a8b168e4ab5e26b9b90fa' 
  AND token = '3wUQ/qbr7rcd8jv7GI8va/Ku2jYCAcB0sZKwwPHIAug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}