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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5f779332133b853028299bb84b2d26c27299a64db13b242912e0e8235f30d9e' 
  AND token = 'ACA+DBNxjPm+46rgquuIzyLgAMHnFspLCYEAqNeK2OI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}