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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34be4f3e8adb6b6771e1e4234fe02d368dfc09ad80734ae52c6356600e23ee14' 
  AND token = '2KK6WwRs6MbyQE+qxcM26KkbRWvgvrDAsNlZXZjWYQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}