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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab3623c2998692036d0ba12829ce047fd9e2927efedb48c858ab2374ab855b41' 
  AND token = 'ziHwuMtqE1l8TXIUIx6N+/VVh/MepE5vEwbyjFe9dIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}