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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a18d3d032cd1188fef21301e5cfcffa57a06444d96b4d9edef14af20a1eb143' 
  AND token = 'oe/ly1D+cfmaP2PUT1IqqM2+dIKpc92DPaeOLEMKd68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}