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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b14d884688bfadf181b710ce202b4b0c060fc92e2332b53ab09871bbd9f10ba' 
  AND token = 'K3INqg/TsD1DApJD3+MQRUwvV6lVyJASQgr3SrggXW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}