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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38bc3ba977de366b874259c2ffdc21c2f9787f65291b436fba8791266fa061fe' 
  AND token = 'dErjvRGIbz1Y2CXdj8FSYrkEyUelcgt22SYQidMLn8U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}