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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed5d09b7c12828e1d3d771c92366f455a3182966ad946bb1b157d7788ad1a7bf' 
  AND token = '+Eub/i++PPKFjhg9hOcjybPlBMK3TcNxc7SUrdyy1+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}