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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0cee8f116cc21c163028c7edc40279559c2ed6ed55d1fa8a0e90706b698ba42' 
  AND token = 'eR+Nsw9rWYQwXBWEEd0qJF31BZOYERcYwmIHBhTQA4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}