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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33fb199205833eb64cbbd575aa95d118c44d5d611a27642c615fc9fe5b215071' 
  AND token = '018uRMYasjy2+40nV4cKD8ATHVXx0GObsXGOz5NWOU8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}