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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18ab0ec76f66b475c4503373a5a0e83079a3b733ccb303d6d01625cb21a361c5' 
  AND token = 'yk0q/5Qs8/1fPxmfYGzZ+E91tS7U9Dlg3PN+1yLb9ek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}