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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cacfb1853195da2b506622791df91550bdcf85960c00e42e5d6f8013e21469e8' 
  AND token = 'Ko78YStm70dOoQvgkfNVJ0BBzJf8gvObTR3ML7mpbNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}