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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ae1b7a8ffd1d8f9af2f159c83939c672ec38d24e6ff8904ad11a6cc80725960' 
  AND token = 'GMaIF6kVwmTnEaVm6hAtAUcVDSZewlEtmE+PUZjB6Qk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}