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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95be9db9ea8cb0622ac6de1684468f33ac4b8fe08c2bdb0c7de942f2ee2069b9' 
  AND token = 'z84TgHhg/s3pVYsF4LrMgEhSVsfEbfSd3rdP8tsmRl4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}