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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ac812bbfb958776cd51a7f1caf26e1535c60f2c12e81aff03be125789267d0d' 
  AND token = 'mfOe1ko+6DJQHRvIkagqDbWYsyYaNPNUWue5XDzrL9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}