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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5adb78de936e03dd9c60fcdab152e23dcecbe1b402b9274cdd084eb1b40f895a' 
  AND token = 'tKZDq5WZvM5aGZ8h3pxOxHHXpGmxSq2mub0fInTp4yw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}