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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75fdccb1b484b08b7e848cbe447c271515432f5d2b583c447576c606628cf982' 
  AND token = 'pQcxaFFQx9xzkddyM6xprs+C8T/069glMCgmYmxovwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}