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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee2378d9c3ddaa810d2c4832f929471a763510bafb5a1742ac1ae0e7707a2843' 
  AND token = 'rdBGKZunnp/roTfhPfQBJoM4i6a5AIRQ+pIJcinVaQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}