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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7317751d4cc260c4a6934ea9a65d896f174b652f1d36449764b79a0cf3a16bd3' 
  AND token = 'vsnuJUbCOKmfzLIjWTHJRMkzfHJGycUsC9yrlc2qcJc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}