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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77d2890c0dbfe9aa09accc104d8c841313676556e100e874ef97888b2d6ff8f8' 
  AND token = 'gEcpJB+Yl7kZ7s3zn48X9zzmGEAXTbjLDGkij6BwVNc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}