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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44fc2647705c62dbf5b77bd62edec5f6c69fbf4d06433877999acdf7854a4048' 
  AND token = 'AVmPMy70yD8FxS0r7nPwDRGyyUGYrLzpqYalZhIEn38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}