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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '001b7e3f7010fc84cf8e39a0baf87c4e99f1265844710a385cce9314fe20f571' 
  AND token = '7BcXwzG0zMv89eBHVnzcEe6wL9HfzzEqf0neL9++UVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}