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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42c75823d8517b954ae04c15ff869da01ea115a82908003c759072cc9cfaec35' 
  AND token = 'tmPiPDgyX9EiRZ27djRhQy4WhD3YenQJ4HDeMzAJ+yU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}