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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e22bc02952fe2fe3b1df67092281c74af5ba0806e8b30a049bc0df2ea6d9ac0b' 
  AND token = 'X6QrP0hOHJwsttzMkTIaE7Row/H2bCF4Wh7Sb6T9tpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}