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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b33ba7b674d68680cc4ce31818713f051aa70dfcc69a37477d3f2a156ee5032' 
  AND token = 'XLOqsk0pXabXcyRowAt7opbi+ey0B3asXNPE2nQWIaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}