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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33b9e9e02ddc5d882d5daab7df22101cdbb68c8d5b07324cdfeac063c1f6310c' 
  AND token = 'QM8pezVbkZYknFQ6toZx9CRql3PUCsL6b3zO2Zp+uN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}