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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2261d86a501342d073d0aa0aa259c8dce4d3566a0a50a00577d88f6dbb930b76' 
  AND token = 'FdMWMDyzKXp47Yr0MfJN+F4gt7LumAw2q/q/U2l7BCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}