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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a418d4e3d43a691ac692dff66ce50ed527c99e9eaf08d2ec61debd4e5925f5a3' 
  AND token = 'CRxPjNAUPcGMOg8KW1wlgnW/I+z0j0SQbHb1FSAxXCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}