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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57b61ce34d0e8538b673cdabf420dea434c38595d8a79194d4ee2a1fcfa4499c' 
  AND token = 'KnOv5pgKfxYNva3brpZMKz736blzUTqN5EcYLG71A9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}