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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '347ed0786f85ac2c7970eaa678a951b11130abe703a7e0b226b03342c65bb8f0' 
  AND token = 'I6IRACuYVnYoJmGiLjLia0tEwP0yTUH6F+orVzEXJU4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}