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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '339fb7c20ce8b1c94d2e9843f96b9a933bafc65fb22a19ea227f15cddb215fe3' 
  AND token = 'CjnnS2/VCKgbN/lCTsDFz4ET6/hGCpm0BoDH4yt62cs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}