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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '220cc15c4789916dec484ad04fd99e96e9a7d06cd0b14d70fe78382fa24e61e1' 
  AND token = 'ziZKRWW2Bob3QO/eZt3i37+PWQUDKEhWXDM3y6xuceY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}