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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64a60b1f22651e91e517356be208ab07d70679a0765c45b099c9d9214c70b82f' 
  AND token = '7R9DVy9/tI7xUmPeRc8RnUp4Ibp1SksOlQ8q0M26nBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}