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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e4069c590747e099a14869f73ae6375de824d1640c4a61f1659f2964bdb0667' 
  AND token = 'lUtax7MtLZDv2ov5NAXfpfdraCuv8ua0oI1RrLpJBec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}