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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51a8054f28dd8ee98a63ebfd720450006c2153250167f2e5ede8dca1e17dd282' 
  AND token = '15hASNvQeT9qlwXj1qjRhqjYTvggkq1d4KZH+nP0bBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}