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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c81a3b72586cde6b627faf75be7295b556182bef3ed2723f622ca6224146e9c' 
  AND token = 'JpI9XS4LBQ2Jl0Z8nTIQu7ZEZk9tyyG/Zsmv8aFx2DE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}