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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a503dcba59a0a5e738a7062abb980d92d9a8116b88bf07ba718a330a9e4c381' 
  AND token = 'sX5WRQCtARjQdT2/9pH7Uj7im7ZBTJw1InDQKs32dFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}