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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77033619547bf2fc48e7354a6b3dbf9c682008acf82a3270e61268ede0a2b0b4' 
  AND token = 'heHx+isY4FM+x67eUGZV0PXmwk4o+ZFiYwyKMFB6c0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}