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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '457b979e5da1164bc1586701118c56c3271790f28dd5ef540e88968bacc8aa02' 
  AND token = 'bEb4Vbe3Q7h8KJ57QrBo3lrDPosv9bDj+fjUR86eBaw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}