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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cef0c78621b27c788ffb95da33872329630c24075ff04baacdc83c30269af4a1' 
  AND token = 'kiy4cFMx3eLaPetUOPdUAnnvBBPIevC3MnuMlmiwGFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}