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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a42e8b638098e584a61b362cd12fbbecefd21682636117244e6d2a4e167c2a8d' 
  AND token = 'zvEU+gAroa8yQISDwq4fOyidoW4HnHsR40NIEs0zLB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}