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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c033545cd36f1a4259ac35c63482ee6477de7caa025c02b44bcb78dfc3786132' 
  AND token = '8Zk8pt07ojZPhtp4vwE6LVyiMGQFjOCPGCtK8tfLKNI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}