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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a910d6f8cfab0eb7c219fac75b7d77d70fc3b17e3e5380958905a5b322c7da42' 
  AND token = 'x7X7pp4uSZ0tlQFwGWoN0r+kXTDZoeRITT1znnV5WdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}