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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f14ea09fd69b7d62b8b50af480fa680c5c58648d7684529d13e269ea4c37c4a6' 
  AND token = 'u/HdpzpExTs+7uHJb0F+xTYWDPHT7g9x/aYz3Aotstc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}