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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1733b2e50ac5ef86c5b507ccd569a338daa8e3f8a6fc30604fb8a4bd55a4f288' 
  AND token = 'jCOR3EUD/d6yh8WJmeXv9d1vYnHyUn1kRol5yMo4AL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}