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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bbabdae9d22a0937f03a497faaed45314a23c9836a8c713960a01a3b04133aa' 
  AND token = '3+6Wu8KSi+9xVrVO86ZrxW13GCRO3K+togR+x9uMAUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}