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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '517b6200f032504fb22eb4dd07af3619476dcd32a8005f9535ed51a0e43f3510' 
  AND token = 'WCujCDnreEFgkp+Vrd7dSGVVCfo6bLAOgxTNwAc56ZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}