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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a150851d6277e20c47e9e67955b05cf4571e7f0595c8987686bc6c698778d873' 
  AND token = 'cQIjt5KF0ZC/soxDRlgDjITsDTmRxqW97EGDJ7wWmCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}